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Press release


Gentle method of diagnosing heart disease

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Study: Computer tomography is extremely dependable

CT-Aufnahme der linken Herzkammer
Dreidimensionale Darstellung der Funktionsanalyse der linken Herzkammer mit der CT (blau eingefärbt) sowohl in der maximalen Füllungsphase (links) als auch der maximalen Auswurfphase des Herzens (rechts) bei einem Patienten mit normaler Funktion.

Computer tomographic images deliver dependable data to analyze the heart’s global pump function. This was shown in a study conducted by radiologists and cardiologists at Charité – Universitätsmedizin in cooperation with the Jena University Hospital. The research results are published in the Journal of the American College of Cardiology*.

In the study, radiologist Privatdozent Dr. Marc Dewey and his work group included every image-producing method available to examine heart function: magnetic resonance imaging (MRI) as a reference standard; 2-D and 3-D echocardiography; coronary catheterization; and computer tomography (CT). With CT, a three-dimensional image was put together using non-invasive x-rays taken from a number of perspectives. The CT resulted in the most dependable data in estimating global pump functions. To detect regional apraxia, computer tomography was just as effective as the other methods in comparison to the MRI.

Furthermore, modern computer tomography enables significantly improved visualization of constricted coronary blood vessels with reduced radiation exposure. “The possibility to evaluate the heart comprehensively and dependably with the CT holds enormous potential,” emphasizes Johannes Greupner from the Institute of Radiology at the Charité Campus Mitte. In cases of specific pain in the chest area, computer tomography can thus become an appropriate non-invasive image-producing procedure. In contrast to the MRI, the CT can also be used on patients with pacemakers without problem.

* Greupner J, Zimmermann E, Grohmann A, Dübel HP, Althoff T, Borges AC, Rutsch W, Schlattmann P, Hamm B, Dewey M.: Head-to-Head Comparison of Left Ventricular Function Assessment with 64-Row Computed Tomography, Biplane Left Cineventriculography, and Both Two- and Three-Dimensional Transthoracic Echocardiography: Comparison with Magnetic Resonance Imaging as the Reference Standard. In: Journal of the American College of Cardiology, Volume 59, Issue 21, 22 May 2012, 1897-1907, DOI: 10.1016/j.jacc.2012.01.046


Click here to read the article in the Journal of the American College of Cardiology.

Institut für Radiologie


Privatdozent Dr. Marc Dewey
Institut für Radiologie
Campus Charité Mitte
Charité – Universitätsmedizin Berlin
t: +49 30 450 527 353

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